Really great for Zoey Samaras:
- boosts her fight,
- boosts her fight with Wither / Spectral Razor / ... if there is a Creature / Monster at the location,
- you spare the action to engage the enemy (if it is engaged with an other investigator) and get an auto-damage with Zoey's Cross,
- gives your the last move you need to enter the location of the enemy Smite the Wicked is attached to.
At 2+ player you can also ask a seeker to play Existential Riddle on a Creature / Monster hunter enemy so that you have the double bonus all the time (as long as you move only one location perround).