
I was excited by this card when I first saw it, but having now finished a campaign as Kate I think it’s only okay-ish. At first glance this card looks like clue acceleration that comes with nifty consolation prizes if you don’t hit the +4 test result for the extra clue, but I quickly realized that I overestimated how often I could force the result I wanted. There were plenty of times I wanted to pick up two clues in a single action (very easy to do with other level 0 cards like Deduction or Fingerprint Kit) but test result just didn’t come out the way I needed.
As it turns out, consistently succeeding by exactly 4 is not easy to manage. Steady-Handed expands the range to 3-5 to get the extra clue and Fine Tuning gives you two attempts per turn, but at this point you’re devoting additional assets (not to mention experience points) to an effect that still isn’t guaranteed to pay out when you need it. It’s worth mentioning that none of these cards are Fast.
With any clue acceleration that relies on Investigate checks you can pull the tentacle and fail, and that’s true of Chemistry Set too, but Chemistry Set has the additional problem that there are lots of other tokens you can pull from the bag that will ensure you get absolutely no benefit from the Chemistry Set at all. The most common way to miss out on a Chemistry Set payout is to pull a token with a larger negative value than you were planning for, but it also feels bad to miss out on the extra clue because you pulled a positive token and got a result that’s too successful to provide a benefit. A levelled up Chemistry Set that exhausts after you pull the token would help avoid a lot of wasted activations and feel-bad moments.
Sure, even when Chemistry Set doesn’t pay out you still get the basic clue from the Investigate test, but that would also be true if I hadn’t spent the action and resources to play Chemistry Set in the first place. Even the tool synergies seem underwhelming, since there are a lot Tools that help you investigate and provide more reliable benefits than the Chemistry Set (such as Lockpicks, Old Keyring, Mariner's Compass, Magnifying Glass, Fingerprint Kit and Ice Pick, to name a few).
To be clear, Chemistry Set paid out cards/resources a few times every scenario I played it, and sometimes even helped me pick up extra clues. It isn’t a terrible card and it does explore interesting new territory for Seeker assets. However, even with multiple support cards in play it often didn't pay out when I needed it to. With the notable exception of Kate and her Science synergy, I think Chemistry Set is more of a novelty than a staple.