In an Agnes Baker or a Lola Hayes deck, the Astronomical atlas can inform you that your weakness is on the top of your deck, which allows you to use Yaotl to discard it from the top of your deck.
Not good enough to include Astronomical atlas if you had planned to use Yaotl, but a good reason to include Yaotl if you had already planned to use the Atlas.
Of course the best solution (to eliminate weaknesses) is Scroll of Secrets (3): look at the bottom 3 cards and discard the weakness among the 3 cards if any. And combined with Astronomical atlas you can even eliminate 2 weaknesses among the 3 cards if necessary (but only Lola and alternate Daisy can have both cards I think).
I've played this game, true solo, a lot for the past year or so but never written a review. This card deserves a raving one! Consider how many locations there are at end game where you need to clear clues to win, usually 2/player. There's an enemy there to mess you up. Game over for him/her/it (!), if you have the health/sanity to give. My advice if you're playing solo: Include it as soon as you can, should you be able to. Finishes scenarios in a hurry.
FYI: If you take both Short Supply and Moonstone, then when your first turn of the game begin, if your Moonstone is one of the ten cards that get discarded, you can immediately play it right from the start. This is quite a neat way to start the game with +1 willpower and + 1 evade. This definitely would be something Patrice Hathaway want to do, but all other investigators who can take both cards should also seriously consider this little combo if they choose to take either Short Supply or vice versa Moonstone, including Lola Hayes (which pumps her willpower and evade to a respectable 4 from the start).
Correction: this does not work because Moonstone needs to be played from your hand.
Just a quick note for beginners: cards in your hand or discard pile are also controlled by you and can be chosen to satisfy the card condition. It doesn't have to be a card in play. (see page 16 in the reference guide)
Almost everybody can take Down the Rabbit Hole now using Versatile and In the Thick of It. Though you don't purchase the cards you swap you should be able to swap Down the Rabbit Hole on and off your deck.
During upgrading you can first upgrade your cards with reduced xp cost, then swap Down the Rabbit Hole for another card an then buy new cards.
During next upgrading do the other way round, first buy then swap and upgrade if necessary.
You could even use Adaptable twice to do it on the same turn.
Or am I wrong and abuse this too much?